Journal: Scientific Reports

Article Title: Effects of β 2 -receptor stimulation by indacaterol in chronic heart failure treated with selective or non-selective β-blockers: a randomized trial

doi: 10.1038/s41598-020-62644-1

Figure Lengend Snippet: Comparison of safety parameters after treatment with placebo or indacaterol in the whole study population.

Article Snippet: Standard ambulatory 24-hour Holter EKG recording was performed through Pathfinder system (Pathinder Digital, Spacelabs Healthcare, Snoqualmie, Washington, USA).

Techniques: Comparison

Journal: bioRxiv

Article Title: EEG-Beats: Automated analysis of heart rate variability (HVR) from EEG-EKG

doi: 10.1101/2020.07.21.211862

Figure Lengend Snippet: Graphical output produced by EEG-Beats. Left: EKG signal acquired using an EEG sensor (blue) for Dataset 1 (Subject S01) of the NCTU RWN_VDE study as described below. Red asterisks show peaks identified by EEG-Beats. Right: EKG peak amplitude versus RR interval size for the peaks on the left (black squares) and right (blue asterisks) ends of each RR interval, respectively. Green lines mark medians and gray lines mark the interquartile ranges in each graph. Dashed gray lines on the right graph indicate the robust outlier limits as defined above. This dataset had no outlier peak amplitudes, so no gray vertical dashed lines appear on the right graph. The vertical axes for the right graph are always fixed to be the range [ rrMinMs, rrMaxMs ].

Article Snippet: Each experiment recorded 62 channels of EEG and one channel of EKG using a Neuroscan headset.

Techniques: Produced

Journal: bioRxiv

Article Title: EEG-Beats: Automated analysis of heart rate variability (HVR) from EEG-EKG

doi: 10.1101/2020.07.21.211862

Figure Lengend Snippet: Dataset 800 (subject S21) of the NCTU RWN_VDE study. Left: the EEG-Beats overlay plot. The gray background curve (axis on the left) shows the EKG signal with the peaks shown as gold asterisks. The RR intervals are plotted as a function of time using black squares (axis to the right). The green line shows the median RR interval. Green ×’s mark RR intervals identified as “bad neighbors”, while the blue circles mark RR intervals with outlier amplitudes using the robust outlier criteria. Right: EKG peak amplitude versus RR interval for the peaks on the left (black square) and right (blue asterisks) ends of the RR interval, respectively. Green lines mark medians, and gray lines mark the interquartile ranges for each variable. Dashed gray lines indicate robust outlier limits. The amplitude axes are truncated at 3.0×IQR outside IQR.

Article Snippet: Each experiment recorded 62 channels of EEG and one channel of EKG using a Neuroscan headset.

Techniques:

Journal: bioRxiv

Article Title: EEG-Beats: Automated analysis of heart rate variability (HVR) from EEG-EKG

doi: 10.1101/2020.07.21.211862

Figure Lengend Snippet: RR interval subplot visualization for Dataset 11 (subject S01) of the NCTU RWN_VDE study (top two graphs). In the top subplot of the visualization, EEG-Beats plots the RR interval lengths versus time as black squares. RRs marked as outliers using the bad neighbor criteria are over-plotted with green ×’s, while RR intervals adjacent to peaks with outlier amplitudes are over-plotted with blue circles. The middle graph plots the EKG signal on the same time line (in gray) with golden asterisks marking the peak positions. The bottom left plot shows an expanded view of a 10-second segment (as indicated by the thick black arrow) using plot overlay form. In this form, the EKG and peaks are plotted using the left axis and the RR interval values and outlier markers use the right axis. The vertical double arrow indicates that the outlier RR with value near 218 seconds is associated with the presence of the extraneous peak. The graph in the lower right corner is the peak versus RR interval graph for the dataset. The extraneous peak appears in the lower right graph as a blue asterisk in the lower left corner (small amplitude peak to the right of a very small RR interval).

Article Snippet: Each experiment recorded 62 channels of EEG and one channel of EKG using a Neuroscan headset.

Techniques:

Journal: bioRxiv

Article Title: EEG-Beats: Automated analysis of heart rate variability (HVR) from EEG-EKG

doi: 10.1101/2020.07.21.211862

Figure Lengend Snippet: Excerpt from Dataset 128 (Subject S03) of the NCTU RWN_VDE study illustrating problematic peaks. Left: EKG signal acquired using an EEG sensor (blue) with red asterisks indicating the peaks identified by EEG-Beats. The vertical arrow at 611 seconds marks a peak labeled as an ambiguous in-range peak during manual checks. The vertical arrow around 620 seconds marks a peak labeled as incorrect. The two adjacent peaks were marked as missed peaks during manual evaluation. Right: EKG peak amplitude versus RR interval for the peaks on the left (black square) and right (blue asterisks) ends of the RR interval, respectively. Green lines mark medians, and gray lines mark the mid quartile boundaries. Dashed gray lines on the right graph indicate the robust outlier limits. The amplitude axis is truncated at 3.0×IQR outside of the mid quartiles. The horizontal arrow marks the point corresponding to the peak marked at 620 seconds in the left graph.

Article Snippet: Each experiment recorded 62 channels of EEG and one channel of EKG using a Neuroscan headset.

Techniques: Labeling